Let’s Dive into Labnet E1110-20MC-1 20 well MC comb for use with 10cm gel system, 1mm thick
In the world of molecular biology, precision is paramount. From setting up a crucial DNA analysis to performing groundbreaking protein studies, the tools we use can either make or break our experiments. The Labnet E1110-20MC-1 20 well MC comb for use with 10cm gel system, 1mm thick promises to offer that precision, designed to work seamlessly with Labnet‘s electrophoresis systems.
My journey to this comb started with a need to optimize my lab’s throughput. We were spending too much time manually preparing gels for our mid-sized DNA fragment analysis, a bottleneck that threatened to slow down several critical research projects. The promise of a 20-well comb that maintains a 1mm thickness – ensuring sufficient sample volume and crisp band resolution – was exactly what I was looking for.
Upon unboxing, my initial impression was one of sturdy simplicity. The comb felt robust, the teeth looked evenly spaced and precisely manufactured. It’s made of what appears to be a durable acrylic material, promising longevity even with frequent use and harsh cleaning protocols.
Compared to the 12-well and 16-well combs we were previously using, this Labnet comb offered a significant increase in sample capacity. We were also using a generic brand comb which demonstrated uneven well formation; hence my preference for Labnet. The Labnet E1110-20MC-1 offered a welcome increase in throughput and a consistent well depth. I was cautiously optimistic, eager to see how it performed in a real-world setting.
Real-World Testing: Putting Labnet E1110-20MC-1 20 well MC comb for use with 10cm gel system, 1mm thick to the Test
First Use Experience
The initial test run was performed in our molecular biology lab, focusing on separating PCR products of varying sizes. I used the comb with the recommended Labnet Enduro Horizontal Gel Box Systems, which ensured compatibility. The gel poured flawlessly, the comb seated snugly, and after polymerization, removal was smooth without tearing the gel – a common issue with cheaper combs.
Performance was excellent. The 1mm thickness provided enough volume to load sufficient DNA, and the wells were perfectly formed, eliminating well-to-well contamination. Even under slightly suboptimal running conditions (a minor voltage fluctuation), the bands were clear and easily distinguishable.
There were no initial surprises, only a sigh of relief that the comb performed exactly as advertised. The well formation consistency exceeded that of our older combs, making the loading process faster and much less prone to error.
Extended Use & Reliability
After several weeks of daily use, the Labnet E1110-20MC-1 has held up admirably. There are no visible signs of wear and tear. This is despite being subjected to multiple washes with various cleaning solutions, including mild detergents and diluted bleach solutions.
Maintenance is a breeze. A simple rinse with deionized water followed by a wipe-down with a lint-free cloth is all that’s needed to keep it clean. I’ve even accidentally dropped it a couple of times (butterfingers, I know), and it hasn’t cracked or chipped.
Compared to the generic combs we used previously, the difference is night and day. The Labnet comb not only produces better results but also requires less maintenance and feels far more robust.
Breaking Down the Features of Labnet E1110-20MC-1 20 well MC comb for use with 10cm gel system, 1mm thick
Specifications
The Labnet E1110-20MC-1 20 well MC comb for use with 10cm gel system, 1mm thick is specifically designed for electrophoresis applications. It is crafted to form 20 individual wells in a gel matrix. The comb itself is constructed from a durable, clear acrylic material for easy visibility.
Each well, created with the comb, maintains a precise 1mm thickness, essential for loading an adequate volume of sample without compromising resolution. The comb is designed to seamlessly integrate with the Labnet Enduro Horizontal Gel Box Systems, specifically those using a 10cm gel. This ensures optimal well spacing and alignment for consistent and reliable electrophoresis.
Performance & Functionality
The Labnet E1110-20MC-1 excels at its primary function: creating consistently sized and shaped wells for gel electrophoresis. This leads to reliable and reproducible results. The uniform 1mm thickness of the wells allows for consistent sample loading, which directly contributes to the clarity and resolution of the resulting bands.
The comb’s greatest strength lies in its ability to increase throughput without sacrificing quality. However, it requires careful handling to avoid scratching the acrylic, which could potentially affect well formation over time. It definitely meets expectations, providing a much-needed boost to our lab’s efficiency.
Design & Ergonomics
The design is straightforward and functional. The clear acrylic material allows for easy visual inspection of the wells during gel pouring, preventing bubbles or imperfections. It is lightweight and easy to handle.
There’s virtually no learning curve. Even a new lab assistant can quickly master its use.
Durability & Maintenance
Constructed from durable acrylic, the Labnet E1110-20MC-1 is designed to withstand repeated use. Proper handling and cleaning are essential to prevent scratches. Regular maintenance involves a simple rinse and wipe-down.
Accessories and Customization Options
The Labnet E1110-20MC-1 is primarily an accessory for the Labnet Enduro Horizontal Gel Box Systems. There are no specific customization options available for the comb itself. However, it is compatible with various gel box sizes and electrophoresis buffer systems, allowing for flexibility in experimental design.
Pros and Cons of Labnet E1110-20MC-1 20 well MC comb for use with 10cm gel system, 1mm thick
Pros
- Increased Throughput: The 20-well design significantly increases the number of samples that can be run simultaneously, saving time and resources.
- Consistent Well Formation: The 1mm thickness ensures uniform well dimensions, which leads to consistent sample loading and high-resolution band separation.
- Durable Construction: The acrylic material is robust and designed to withstand repeated use and cleaning, offering long-term value.
- Easy to Use: The straightforward design requires minimal training, making it accessible to both experienced and novice users.
- Seamless Integration: Specifically designed for Labnet Enduro systems, it ensures perfect compatibility and optimal performance.
Cons
- Scratch Sensitivity: The acrylic material is prone to scratches if not handled carefully, which can affect well formation over time.
- System Dependence: While it integrates seamlessly with Labnet systems, it might not be compatible with gel boxes from other manufacturers.
Who Should Buy Labnet E1110-20MC-1 20 well MC comb for use with 10cm gel system, 1mm thick?
Perfect for molecular biology labs, genetic research facilities, and biochemistry departments looking to increase the efficiency of their gel electrophoresis processes. It’s a must-have for researchers working with mid-sized DNA fragments, RNA samples, or proteins where high throughput and clear band resolution are crucial.
Those who primarily work with very small or very large DNA fragments might find a different comb with narrower or wider wells more suitable. Additionally, if you are not using Labnet gel electrophoresis systems, compatibility should be carefully considered.
Must-have accessories include a high-quality gel electrophoresis apparatus (Labnet Enduro Horizontal Gel Box Systems are highly recommended), electrophoresis buffer, and a reliable power supply. A soft, lint-free cloth for cleaning is also essential to maintain the comb’s surface and prevent scratches.
Conclusion on Labnet E1110-20MC-1 20 well MC comb for use with 10cm gel system, 1mm thick
The Labnet E1110-20MC-1 20 well MC comb for use with 10cm gel system, 1mm thick is a valuable addition to any molecular biology lab seeking to optimize their gel electrophoresis workflow. Its consistent well formation, durable construction, and ease of use make it a clear winner in terms of both performance and convenience. The value proposition is solid: for $77.99, you’re investing in a tool that will save you time, improve your results, and last for years to come.
I personally recommend it without hesitation. If you are using a Labnet Enduro system and need to increase your sample throughput while maintaining high-quality results, this comb is an excellent choice. Don’t let inefficient gel preparation slow down your research – invest in the Labnet E1110-20MC-1 and experience the difference.