Let’s Dive into Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm
The Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm represent a crucial tool for researchers focused on cell culture. Corning has a long-standing reputation for providing reliable and high-quality lab equipment, and this product appears to be no exception with its collagen coating designed to enhance cell attachment and growth.
As a seasoned specialist, I’ve seen firsthand the frustration of inconsistent cell cultures due to poor adherence. I needed a reliable, large-format culture dish for a series of hepatocyte studies demanding uniform cell attachment across a large surface area.
Upon unboxing, the dishes felt sturdy and well-packaged, a good initial sign of Corning’s attention to detail. The clarity of the polystyrene was impressive, allowing for excellent microscopic visibility.
Compared to standard, uncoated culture dishes and other collagen-coated brands, I was looking for a specific combination of size, proven collagen coating, and a history of consistent performance. While other dishes might offer similar features, Corning’s reputation and the reported stability of the collagen coating swayed my decision.
My first impression was optimistic; the dishes looked like a solid, professional-grade tool that could truly improve the reliability of my cell culture experiments. The promise of enhanced cell attachment was definitely exciting.
Real-World Testing: Putting Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm to the Test
First Use Experience
I tested the Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm in our cell culture lab, specifically for culturing primary hepatocytes. The dishes were used under standard cell culture conditions: 37°C, 5% CO2, and humidified atmosphere, with specialized hepatocyte culture medium.
The Corning dishes performed exceptionally well even with slight variations in media formulation. Cell attachment was noticeably improved compared to uncoated dishes, even under standard conditions.
The dishes required no special preparation beyond standard sterile techniques. Handling was straightforward, and the large surface area made seeding and observation particularly convenient.
Initially, I was concerned about potential inconsistencies in the collagen coating, but cell attachment was remarkably uniform across the entire dish surface. There were no surprises.
Extended Use & Reliability
After several weeks of continuous use, the Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm have consistently delivered reliable results. Cell morphology remained stable and healthy, a critical factor for my long-term experiments.
The dishes exhibited no signs of degradation or coating detachment over the extended culture period. They appear durable.
Maintenance was simple: standard media changes and microscopic observations were all that was required. They are easy to clean.
Compared to my previous experiences with uncoated dishes and some other collagen-coated brands, the Corning dishes have significantly improved cell attachment, growth, and overall culture consistency. They outperform my expectations.
Breaking Down the Features of Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm
Specifications
The Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm feature a 150 mm diameter culture surface. They are coated with a uniform layer of fibrillar Collagen I.
The BD No. (catalog number) for this product is 354551. They are designed to be stable for six months from the date of shipment when stored at 2 to 8°C (36 to 46°F).
The 150 mm size provides ample space for cell proliferation and differentiation. The Collagen I coating mimics the extracellular matrix, promoting better cell attachment and viability.
Performance & Functionality
The Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm excel in providing a consistent and reliable surface for cell culture. Cell attachment is significantly enhanced, leading to improved growth and differentiation.
A major strength is the uniformity of the collagen coating; however, the price point might be a concern for some labs. They exceed expectations.
Design & Ergonomics
The dishes are made of high-quality polystyrene, ensuring optical clarity and mechanical strength. Their weight is standard for a dish of this size, and they are comfortable to handle.
The design is user-friendly with standard dimensions compatible with most cell culture incubators and microscopes. The large surface area simplifies seeding and observation.
Durability & Maintenance
The polystyrene construction ensures good physical durability under normal lab conditions. The collagen coating remains stable under recommended storage and usage conditions.
Maintenance involves standard cell culture procedures, such as media changes and microscopic analysis. The dishes are generally disposable, eliminating the need for extensive cleaning.
Accessories and Customization Options
The Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm are primarily used as a standalone cell culture vessel and do not require additional specialized accessories. However, standard cell culture reagents like media, supplements, and growth factors are essential for optimal performance.
They are compatible with various cell imaging and analysis systems. There are no specific customization options for the dishes themselves.
Pros and Cons of Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm
Pros
- Enhanced Cell Attachment: The Collagen Type I coating significantly improves cell adherence and spreading, leading to healthier cultures.
- Consistent Performance: The uniform coating ensures reproducible results across multiple experiments.
- Large Surface Area: The 150 mm diameter provides ample space for cell proliferation and differentiation.
- High-Quality Materials: The polystyrene construction ensures optical clarity and mechanical strength.
- Reduced Detachment: Reduces cell detachment compared to uncoated dishes.
Cons
- Price: The cost per dish is relatively high compared to uncoated alternatives, which might be a barrier for some labs.
- Storage Requirements: Requires storage at 2 to 8°C to maintain coating stability.
Who Should Buy Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm?
Perfect for researchers working with cell types that are difficult to adhere to standard culture surfaces. Researchers who require consistent and reliable cell attachment for downstream analysis. These are also great for labs focused on hepatocyte culture, endothelial cell research, and muscle cell studies.
Researchers who can afford the premium price for enhanced cell culture performance will benefit. Those on a very tight budget may need to consider uncoated alternatives.
Must-have accessories include high-quality cell culture media, appropriate growth factors, and sterile cell culture handling equipment. No modifications are necessary for standard use.
Conclusion on Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm
The Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm are a valuable tool for any cell culture lab aiming for consistent and reliable results. The enhanced cell attachment provided by the Collagen Type I coating translates to healthier and more reproducible cultures.
The price is indeed higher than standard dishes, but the improved performance justifies the investment, especially for critical experiments and cell types that require enhanced adhesion.
I would highly recommend the Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm to any researcher looking to elevate their cell culture game. Invest in the Corning BioCoat Cellware, Collagen Type I, 354551 Culture Dishes 150 Mm today, and experience the difference in your cell culture experiments!