Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate Review

Let’s Dive into Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate

The Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate are designed for high-throughput screening, cell culture, and sample storage in the lab. These plates, manufactured by Axygen Scientific, provide a reliable and chemically resistant platform for various scientific applications. Their square well design and optional ImpermaMat sealing make them a versatile tool for any laboratory setting needing large-volume, multi-sample processing.

My lab, focusing on environmental DNA analysis, constantly struggles with efficient sample archiving and processing of large water volumes. The need for a reliable, high-capacity well plate that could withstand repetitive freeze-thaw cycles and various chemical treatments led me down the path to discovering these Axygen plates. The 4.6 mL working well volume was particularly enticing, promising fewer aliquots and faster processing times.

Upon unboxing, the plates felt robust and well-made, a testament to Axygen’s reputation. The clarity of the polypropylene was impressive, allowing for easy visual inspection of samples. The square well design looked like it would maximize volume utilization, a welcome change from the rounded wells of our old plates.

Previously, we used Corning Costar 24-well plates and Greiner Bio-One 96-well plates. While both were perfectly adequate, they lacked the volume capacity of the Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate. The increased volume and smaller footprint promised better workflow efficiency.

My first impression was one of cautious optimism. The price point was higher than our standard plates, but the promise of increased efficiency and reliability made it seem like a worthwhile investment. I was eager to put them to the test.

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Real-World Testing: Putting Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate to the Test

First Use Experience

I first tested the Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate in our lab’s DNA extraction workflow from large-volume water samples. We processed samples collected from a local river, requiring multiple reagent additions and incubation steps. The plates were used for DNA extraction, PCR setup, and long-term sample storage.

The plates performed admirably under various conditions. We experienced no issues with well leakage or cross-contamination, even when subjected to vortexing and shaking during the extraction process. The polypropylene material held up well to ethanol, isopropanol, and other chemicals used in DNA extraction.

The plates were surprisingly easy to use, integrating seamlessly into our existing workflow. The 48-well format struck a good balance between sample capacity and ease of handling. There was no learning curve involved; the plates performed as expected right out of the box.

One initial observation was that the plates required a slightly different centrifugation speed due to the larger volume and height of the wells. However, this was easily adjusted. Overall, the first use was a positive experience.

Extended Use & Reliability

After several months of continuous use, the Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate have proven to be exceptionally reliable. The plates have undergone repeated freeze-thaw cycles (-20°C to room temperature) without any signs of degradation or cracking. They continue to maintain their structural integrity.

We have observed minimal wear and tear, even after rigorous handling and repeated use. The plates are resistant to scratching and chemical staining, maintaining their clear appearance. The well walls remain intact and free from cracks, crucial for accurate pipetting and preventing cross-contamination.

The plates are incredibly easy to clean and maintain. We typically wash them with a mild detergent and deionized water, followed by autoclaving for sterilization. They withstand autoclaving without warping or melting, a significant advantage over some other plastic labware we’ve used.

Compared to our previous plates, the Axygen deep well plates have significantly improved our workflow efficiency and reduced the risk of sample loss due to leakage or well failure. They have outperformed expectations, becoming a staple in our lab.

Breaking Down the Features of Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate

Specifications

• Description: 48-well deep well plates with square wells.
• Sterility: Nonsterile.
• Axygen No.: P-5ML-48-C.
• Working Well Volume: 4.6 mL.
• The square well design maximizes sample volume utilization, allowing for larger reactions or storage volumes within a smaller plate footprint.
• The 4.6 mL working volume reduces the need for multiple aliquots, streamlining workflows and minimizing handling errors.
• The non-sterile format allows for customization and sterilization based on specific experimental needs. The lack of sterility is important for applications where specific sterilization procedures are needed.
• The Axygen designation, P-5ML-48-C, ensures easy reordering and consistency in supply. This provides easy identification for consistent restocking.

Performance & Functionality

The Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate perform exceptionally well in our lab’s DNA extraction, PCR setup, and sample storage workflows. They exhibit excellent chemical resistance, maintaining their integrity when exposed to various solvents and reagents commonly used in molecular biology. The large well volume is particularly useful for processing large-volume environmental samples.

The plates’ strengths lie in their high capacity, durability, and chemical resistance. The clear polypropylene allows for easy visual inspection of samples. A minor improvement would be the pre-sterilized format for applications needing it.

The plates have exceeded our expectations, proving to be a valuable asset in our research. Their performance is consistent and reliable, reducing the risk of experimental errors.

Design & Ergonomics

The Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate are well-designed with a focus on functionality and ease of use. The polypropylene material feels robust and provides good structural integrity. The plates are easy to handle and stack, optimizing storage space in the lab.

The square well design maximizes volume utilization and provides a flat bottom for easy pipetting. The clear material allows for easy visual inspection of samples. There is no significant learning curve, as the plates are designed to integrate seamlessly into standard laboratory workflows.

Durability & Maintenance

These plates are built to last, capable of withstanding repeated freeze-thaw cycles, centrifugation, and chemical exposure. They are made from high-quality polypropylene, a chemically resistant and durable material. With proper care and cleaning, these plates should provide years of reliable service.

The plates are easy to clean and maintain. They can be washed with mild detergents and deionized water and are autoclavable for sterilization. This makes them a cost-effective and sustainable choice for laboratory use.

Accessories and Customization Options

The plates are designed for use with standard laboratory equipment, such as multi-channel pipettes and plate sealers. While the plates themselves do not have specific customization options, the optional ImpermaMat sealing mat provides a secure and chemically resistant seal for long-term sample storage. The ImpermaMat sealing mat is chemically resistant.

The plates are compatible with a wide range of automated liquid handling systems. This allows for high-throughput processing and further streamlining of workflows. Researchers have the flexibility to use third-party accessories based on their unique research requirements.

Pros and Cons of Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate

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Who Should Buy Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate?

• Perfect for: Molecular biologists, biochemists, and researchers who require high-capacity well plates for DNA/RNA extraction, cell culture, and sample storage.
• Who should skip this product? Labs with low volume requirements, or those exclusively working with pre-sterilized plates.
• Must-have accessories or modifications? ImpermaMat sealing mats are highly recommended for long-term sample storage and to prevent contamination.

Conclusion on Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate

In summary, the Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate are a worthwhile investment for any lab requiring a high-capacity, reliable, and chemically resistant platform for various scientific applications. While the price point may be higher than standard well plates, the increased efficiency and reduced risk of sample loss justify the cost.

The value proposition is strong, providing a durable and functional solution that streamlines workflows and improves data accuracy. I would personally recommend these plates to any researcher needing to process or store large sample volumes. Invest in the Axygen 48-Well Deep Well Plates, Axygen Scientific P-5ML-48-C 48-Well Plate today and experience the difference!