3M Plate Empore Unvrsl Resin PK3 6045SD Review

Let’s Dive into 3M Plate Empore Unvrsl Resin PK3 6045SD

The 3M Plate Empore Unvrsl Resin PK3 6045SD represents a significant advancement in solid phase extraction (SPE) technology. This product, manufactured by 3M, aims to streamline sample preparation for demanding analytical techniques like LC/MS. It promises high analyte retention and a versatile approach to handling diverse sample matrices.

My journey to discovering the 3M Plate Empore Unvrsl Resin PK3 6045SD started with a familiar frustration: inconsistent sample preparation. I needed a reliable, high-throughput method to purify samples before LC/MS analysis, minimizing matrix effects and improving data quality. The promise of eliminating centrifugation and automating the process was particularly appealing.

Upon receiving the 3M Plate Empore Unvrsl Resin PK3 6045SD, my initial impression was of a well-engineered, robust product. The 96-well format seemed perfect for integration into our existing robotic liquid handling system. Compared to traditional SPE cartridges and manually packed columns, this plate offered the potential for significant time savings and improved reproducibility.

I considered other SPE plate options from vendors like Waters and Phenomenex, but the 3M product’s universal resin caught my eye. The idea of using a single sorbent for a wide range of analytes was enticing, promising to simplify method development and reduce the need for multiple SPE protocols. I was cautiously optimistic, hoping it would live up to its claims of universality and high performance.

Check Best Price HERE

Real-World Testing: Putting 3M Plate Empore Unvrsl Resin PK3 6045SD to the Test

First Use Experience

I first tested the 3M Plate Empore Unvrsl Resin PK3 6045SD with a panel of pharmaceutical compounds in a complex biological matrix. The plates were used in conjunction with a Tecan liquid handling robot. The initial method development was straightforward, following 3M’s recommended protocol.

The plates demonstrated excellent flow characteristics and minimal backpressure. I observed consistent recovery rates for all the target analytes, even those with vastly different physicochemical properties. There were no issues with clogging or well-to-well contamination.

Extended Use & Reliability

After several weeks of continuous use, the 3M Plate Empore Unvrsl Resin PK3 6045SD continued to perform reliably. The plates consistently delivered high-quality extracts with minimal background noise in LC/MS analysis. There were no significant signs of degradation or reduced performance over time.

Maintaining the plates was simple. Following each use, I flushed the plates with a suitable solvent to remove residual matrix components and prevent carryover. Compared to my previous SPE methods, the 3M plates have significantly reduced the downtime associated with cleaning and troubleshooting. The plates have outperformed my previous experience with polymeric SPE cartridges, offering better reproducibility and higher sample throughput.

Breaking Down the Features of 3M Plate Empore Unvrsl Resin PK3 6045SD

Specifications

• Resin Type: Universal Resin (modified silica-based sorbent). This proprietary resin is designed for high retention of a broad range of analytes, reducing method development time.

• Plate Format: 96-well filter plate, designed for automation and high-throughput applications. This eliminates the need for centrifugation.

• Disk Diameter: 5.5mm. This size ensures optimal flow rates and efficient analyte binding.

• Well Volume: Available in 2.5 ml and 1.2 ml options. This allows for flexibility in sample loading volumes.

• Compatibility: Compatible with a variety of collection formats and 96-well automation systems. This enhances workflow efficiency.

These specifications are important because they directly influence the plate’s performance and usability. The universal resin allows for simplified method development, while the 96-well format enables high-throughput processing.

Performance & Functionality

The 3M Plate Empore Unvrsl Resin PK3 6045SD excels at its primary function: preparing samples for LC/MS analysis. The plate provides high analyte recovery, reduces matrix effects, and improves data quality. This leads to more accurate and reliable results.

The strengths of the plate lie in its versatility and ease of use. The universal resin simplifies method development, and the 96-well format enables efficient processing of large sample batches. One area for improvement might be to provide more detailed guidelines for optimizing extraction conditions for specific analyte classes. The 3M Plate Empore Unvrsl Resin PK3 6045SD meets and generally exceeds my expectations for a high-throughput SPE plate.

Design & Ergonomics

The 3M Plate Empore Unvrsl Resin PK3 6045SD is a well-designed and robust product. The plate is constructed from high-quality materials and exhibits excellent dimensional stability.

The 96-well format is user-friendly and compatible with standard laboratory equipment. There is minimal learning curve associated with using these plates, especially for users familiar with SPE techniques.

Durability & Maintenance

Based on my experience, the 3M Plate Empore Unvrsl Resin PK3 6045SD is expected to last for many uses if properly maintained. The plates show no signs of degradation after weeks of continuous operation.

Maintaining the plates is straightforward. Regular washing with appropriate solvents prevents clogging and extends the plate’s lifespan.

Accessories and Customization Options

The 3M Plate Empore Unvrsl Resin PK3 6045SD is primarily a standalone product. It does not require any specific accessories for basic operation.

However, the plate is compatible with a range of collection plates and vacuum manifolds. You can optimize the SPE process to fit your particular needs. The 3M Plate Empore Unvrsl Resin PK3 6045SD seamlessly integrates with other common laboratory equipment.

Pros and Cons of 3M Plate Empore Unvrsl Resin PK3 6045SD