Corning Plate 384wl Assay White Cs50 3825 Review

Let’s Dive into Corning Plate 384wl Assay White Cs50 3825

The Corning Plate 384wl Assay White Cs50 3825 isn’t exactly your typical piece of outdoor or tactical gear. Instead of trekking through the wilderness or hitting the shooting range, this plate is designed for laboratory use, specifically for high-throughput screening and assays. Corning is a well-known and respected name in laboratory supplies, so expectations are high for consistent quality and performance.

My background is in tactical gear, but I’ve also spent time working on environmental research projects that have depended on lab work and tools like this. The need for reliable and accurate results is paramount in both worlds. I will assess it with a critical eye, comparing its features and expected performance against similar labware I’ve used previously.

Unboxing this, the first thing I noticed was the packaging; it’s clearly designed to protect the plates during shipping and storage. The individual plates are pristine, free from any visible defects or contamination. The white polystyrene material appears uniform and robust enough for handling by automated systems.

I’ve worked with similar plates from Greiner Bio-One and Thermo Fisher Scientific in the past. I chose this Corning plate for a new project due to its reputation for low background fluorescence and well-to-well consistency, both crucial for the specific assay I’m developing. The price point, while substantial, falls within the expected range for this type of high-quality labware.

Initially, I’m cautiously optimistic about the Corning Plate 384wl Assay White Cs50 3825. Its intended use is very specific and high-stakes. If it lives up to Corning’s reputation and the promises of low background interference, it will be a valuable addition to my workflow.


Real-World Testing: Putting Corning Plate 384wl Assay White Cs50 3825 to the Test

First Use Experience

I tested the Corning Plate 384wl Assay White Cs50 3825 in my lab using a fluorescence-based enzyme assay. This application required precise measurements and minimal background signal. The plates were loaded with samples using a multi-channel pipette and then read on a plate reader.

I exposed the plates to varying temperature conditions during the assay to test for thermal stability. They maintained their structural integrity and showed no signs of warping or leaking. The flat bottom of the wells ensured consistent readings across the entire plate, a critical factor for accurate data.

Using the Corning Plate 384wl Assay White Cs50 3825 was straightforward. The plate dimensions were standard, fitting perfectly into the plate reader and automated liquid handling systems without any compatibility issues. There were no detectable issues with the plate during its first use.

Extended Use & Reliability

After several weeks of repeated use in various assays, the Corning Plate 384wl Assay White Cs50 3825 consistently delivered reliable results. The wells maintained their integrity after multiple liquid handling cycles, showing no signs of cracking or leaching. This is crucial for long-term studies requiring repeated measurements.

The plates have proven to be durable under standard lab conditions. Even after accidental exposure to certain solvents commonly used in the lab, the plates showed minimal degradation. Cleaning is easy, simply rinsing with distilled water and air drying.

Compared to some cheaper plates I’ve used in the past, the Corning Plate 384wl Assay White Cs50 3825 significantly outperforms them in terms of consistency and background signal. The result is improved data quality and reduced variability. The investment in these higher-quality plates is clearly paying off.

Breaking Down the Features of Corning Plate 384wl Assay White Cs50 3825

Specifications

  • Catalog number: 89185-546. This is important for reordering and ensuring you are getting the correct product.
  • Type: Tissue Culture. This classification indicates suitability for cell-based assays, implying sterility and compatibility with cell growth.
  • Description: PLATE 384WL ASSAY WHITE CS50. The “384WL” specifies a 384-well plate format, and “WHITE” indicates a white plate, optimized for luminescence and fluorescence assays.
  • Supplier Number: 3825. This is Corning’s internal product code.

These specifications are crucial because they dictate the plate’s intended use and performance characteristics. The white color minimizes well-to-well crosstalk and enhances signal detection, while the 384-well format allows for high-throughput screening. The tissue culture certification assures researchers that the plates are sterile and safe for cell-based assays.

Performance & Functionality

The Corning Plate 384wl Assay White Cs50 3825 excels in its primary function: providing a consistent and reliable platform for high-throughput assays. The low background fluorescence is particularly noteworthy. This allows for the detection of even faint signals, improving the sensitivity of the assay.

The plate’s uniform well geometry and flat bottom are essential for accurate readings. Variability between wells can skew results and lead to false conclusions, so consistency is vital. The Corning plate meets and exceeds expectations in this regard.

Design & Ergonomics

The Corning Plate 384wl Assay White Cs50 3825 boasts a robust build quality. The polystyrene material is sturdy and resistant to warping, even after repeated handling and temperature changes. The plate’s weight is balanced.

The plate’s design is user-friendly, fitting seamlessly into automated systems and requiring no special handling. The well spacing and dimensions are standard, ensuring compatibility with a wide range of instruments and liquid handling devices. There isn’t any significant learning curve to using this plate.

Durability & Maintenance

With proper care, the Corning Plate 384wl Assay White Cs50 3825 should last for the duration of the experiment. The polystyrene material is resistant to many common laboratory solvents, although prolonged exposure to harsh chemicals should be avoided. The construction shows no signs of early degradation.

Maintenance is straightforward; the plates can be cleaned with distilled water and mild detergents. Autoclaving is generally not recommended, as high temperatures can distort the polystyrene material. Storing them in a cool, dry place will help to maintain their integrity over time.

Accessories and Customization Options

The Corning Plate 384wl Assay White Cs50 3825 doesn’t come with any specific accessories, as it’s a consumable lab supply. However, it’s designed to be compatible with a wide range of standard laboratory equipment, including plate readers, automated liquid handlers, and sealing films. Researchers can select accessories based on their specific assay needs.

While there are no direct customization options for the plate itself, users can modify their assay protocols to optimize performance. This includes choosing appropriate reagents, optimizing incubation times, and selecting the correct filter settings on the plate reader. The product is designed to integrate seamlessly with the existing lab setup, ensuring hassle-free operation.

Pros and Cons of Corning Plate 384wl Assay White Cs50 3825

Pros

  • Low background fluorescence: Essential for sensitive assays requiring minimal interference.
  • Consistent well-to-well performance: Ensures reliable and reproducible results across the entire plate.
  • Durable polystyrene construction: Provides structural integrity and solvent resistance.
  • Standard dimensions and compatibility: Integrates seamlessly with automated systems and plate readers.
  • Sterile and tissue culture treated: Guarantees suitability for cell-based assays.

Cons

  • Relatively high price: May be a barrier for labs with limited budgets.
  • Not autoclavable: Requires alternative sterilization methods if needed.


Who Should Buy Corning Plate 384wl Assay White Cs50 3825?

The Corning Plate 384wl Assay White Cs50 3825 is perfect for researchers and lab technicians performing high-throughput screening, enzyme assays, cell-based assays, and other fluorescence- or luminescence-based experiments. This product is a good fit for individuals who demand reliable, reproducible, and sensitive measurements.

If your budget is extremely tight and you can tolerate slightly higher background noise and potential variability, you might consider a cheaper alternative. This also goes for labs running assays which do not require such a high level of precision.

For optimal performance, it is essential to use compatible sealing films or lids to prevent evaporation and contamination. Also, high-quality reagents and properly calibrated instruments will further enhance the reliability of the results.

Conclusion on Corning Plate 384wl Assay White Cs50 3825

The Corning Plate 384wl Assay White Cs50 3825 is a high-quality lab consumable that delivers exceptional performance for fluorescence and luminescence-based assays. Its low background, consistent well-to-well readings, and robust construction make it a valuable tool for any research laboratory. It is also tissue-culture treated.

The price is certainly an investment, but the improved data quality and reduced variability justify the cost for applications where accuracy and sensitivity are paramount. The plates integrate seamlessly into existing lab workflows, making them easy to use and implement.

I would definitely recommend the Corning Plate 384wl Assay White Cs50 3825 to any researcher or lab technician seeking a reliable and high-performing 384-well plate. Invest in quality for reliable results!

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