Let’s Dive into VWR Comb 12 Well 1.5MM Page E2110-12-1.5
The VWR Comb 12 Well 1.5MM Page E2110-12-1.5 is, at first glance, a deceptively simple tool. However, for anyone working in a lab environment where precise sample handling is crucial, this comb represents a significant upgrade in efficiency and reliability, especially in applications like gel electrophoresis. VWR, a well-respected name in laboratory supplies, promises a durable and chemically resistant product designed for repeated use.
My journey with lab equipment started years ago, often involving makeshift solutions and compromises. Specifically, I needed a reliable way to create uniform wells in gels for DNA and protein analysis, something that was consistently reproducible. The inconsistent well sizes created with older, less precise methods were causing inaccurate results and wasted valuable reagents.
Upon unboxing the VWR Comb 12 Well 1.5MM Page E2110-12-1.5, I immediately noticed the solid construction and the rigidity of the polypropylene material. The octagonal shape felt surprisingly comfortable in my hand, and the well spacing appeared perfectly consistent. It felt far more robust than the flimsy acrylic combs I’d used previously.
Compared to standard, generic gel combs I’ve used from Amazon and the fragile, hand-crafted ones some colleagues insist on making, this VWR comb looked like a precision instrument. The alternatives often lack chemical resistance, warping or even dissolving upon contact with certain buffer solutions. I chose the VWR Comb 12 Well 1.5MM Page E2110-12-1.5 for its promise of durability and resistance to harsh chemicals, and the fact that it comes with a specification sheet that details the exact dimensions of each well.
My first impression was relief; this looked like a tool built to last and deliver consistent results. The price tag, while higher than some generic options, seemed justified given the potential for improved data and reduced reagent waste.
Real-World Testing: Putting VWR Comb 12 Well 1.5MM Page E2110-12-1.5 to the Test
First Use Experience
I first tested the VWR Comb 12 Well 1.5MM Page E2110-12-1.5 during a routine DNA electrophoresis run in our molecular biology lab. The comb was used to create wells in a 1.5% agarose gel for loading PCR products. The lab environment is generally temperature controlled, but humidity can fluctuate.
Even under slightly humid conditions, the comb slid effortlessly into the gel without distorting the surrounding matrix. The wells formed were perfectly uniform and clearly defined, unlike the misshapen and often tearing wells I had experienced before. No extra time was needed to adjust to the comb.
There were no immediate issues; the VWR Comb 12 Well 1.5MM Page E2110-12-1.5 performed as expected, producing consistent wells and simplifying the loading process. It was a refreshing change from the usual struggle with inferior combs.
Extended Use & Reliability
After several weeks of consistent use, the VWR Comb 12 Well 1.5MM Page E2110-12-1.5 has held up remarkably well. There are no visible signs of wear or deformation despite repeated exposure to electrophoresis buffers, ethidium bromide, and UV light. The solid polypropylene construction shows no sign of degradation.
Maintenance is simple: a quick rinse with distilled water followed by air drying is all that’s needed to keep the comb clean and ready for the next use. Compared to my previous experience with acrylic combs that cracked and became brittle, the VWR Comb 12 Well 1.5MM Page E2110-12-1.5 is a clear winner in terms of durability and ease of maintenance. It far outperforms the cheaper alternatives.
Breaking Down the Features of VWR Comb 12 Well 1.5MM Page E2110-12-1.5
Specifications
The VWR Comb 12 Well 1.5MM Page E2110-12-1.5 features 12 wells with a thickness of 1.5mm, designed for optimal sample loading in gel electrophoresis. Its construction consists of high-quality polypropylene, ensuring resistance to acids, alkalis, and common laboratory chemicals. The octagonal shape of the comb body allows for a comfortable and secure grip.
The 1.5mm thickness is crucial for achieving adequate sample volume in each well, providing clear and distinct bands during electrophoresis. The polypropylene material guarantees that the comb will not corrode or react with the chemicals used in the electrophoresis process.
Performance & Functionality
The VWR Comb 12 Well 1.5MM Page E2110-12-1.5 excels in creating uniform and well-defined wells in electrophoresis gels, which is essential for accurate sample loading and analysis. Its main strength lies in its ability to produce consistent results, eliminating the variability often seen with cheaper combs. It meets and exceeds expectations.
The only potential weakness could be the limited number of wells for labs that routinely run high-throughput electrophoresis. However, for most standard applications, 12 wells provide sufficient capacity.
Design & Ergonomics
The VWR Comb 12 Well 1.5MM Page E2110-12-1.5 features an octagonal design, which provides a secure and comfortable grip, allowing for precise placement in the gel. The build quality is excellent, with the high-quality polypropylene providing a robust and durable feel. It is user-friendly with virtually no learning curve.
The comb’s weight is balanced, allowing for smooth and even insertion into the gel. The wells are evenly spaced, ensuring optimal sample separation during electrophoresis.
Durability & Maintenance
The VWR Comb 12 Well 1.5MM Page E2110-12-1.5 is built to last, with its high-quality polypropylene construction designed to withstand repeated use and exposure to harsh chemicals. With proper care and maintenance, it should provide years of reliable service. Cleaning is simple: a quick rinse with distilled water and air drying is all that’s needed.
Due to its chemical resistance, there’s no risk of corrosion or degradation with normal lab use. The material is resilient and unlikely to crack or warp.
Accessories and Customization Options
The VWR Comb 12 Well 1.5MM Page E2110-12-1.5 does not come with any additional accessories, as it’s a standalone tool. The key is its compatibility with standard electrophoresis setups. While not customizable in the traditional sense, its consistent dimensions make it easy to integrate with existing gel casting systems and electrophoresis chambers.
Its standardized design ensures that it works seamlessly with a wide range of gel sizes and buffer systems. Aftermarket well-sealant solutions (if desired to prevent leakage of sample during incubation, for example) from other brands are commonly compatible.
Pros and Cons of VWR Comb 12 Well 1.5MM Page E2110-12-1.5
Pros
- Consistent and uniform well formation, leading to accurate and reproducible results.
- High-quality polypropylene construction, ensuring durability and chemical resistance.
- Ergonomic octagonal design for a comfortable and secure grip.
- Simple maintenance and cleaning.
- Long lifespan with proper care.
Cons
- Relatively higher price compared to generic combs.
- Limited number of wells (12) might not be sufficient for high-throughput applications.
Who Should Buy VWR Comb 12 Well 1.5MM Page E2110-12-1.5?
The VWR Comb 12 Well 1.5MM Page E2110-12-1.5 is perfect for molecular biology labs, biochemistry labs, and any research environment where gel electrophoresis is a routine procedure. Researchers, lab technicians, and students who require consistent and reliable well formation for accurate sample loading will benefit the most. Anyone who wants to eliminate variability and improve the quality of their electrophoresis data will find it an indispensable tool.
Labs focused on high-throughput screening and those with extremely limited budgets might consider alternative options. However, the long-term cost savings from reduced reagent waste and improved data quality often outweigh the initial price difference.
A must-have is proper gel casting system to ensure the gel is properly set before using the comb. An accurate micropipette to ensure uniform sample loading into wells after the comb is used is required to obtain the best data.
Conclusion on VWR Comb 12 Well 1.5MM Page E2110-12-1.5
In summary, the VWR Comb 12 Well 1.5MM Page E2110-12-1.5 is a reliable, durable, and precise tool that significantly improves the efficiency and accuracy of gel electrophoresis. The higher price is justified by its superior performance, long lifespan, and the reduction in reagent waste.
I would personally recommend it to any lab that values data quality and consistency. It is a worthwhile investment that pays for itself over time through improved results and reduced errors.
Don’t settle for subpar gel combs that compromise your data; invest in the VWR Comb 12 Well 1.5MM Page E2110-12-1.5 and experience the difference in your electrophoresis results. Upgrade your lab equipment today!