VWR Maxi 20 Electrophoresis System E1120-20MC-1 Combs 1 Mm x 20-Tooth Comb Review

Let’s Dive into VWR Maxi 20 Electrophoresis System E1120-20MC-1 Combs 1 Mm x 20-Tooth Comb

The VWR Maxi 20 Electrophoresis System E1120-20MC-1 Combs 1 Mm x 20-Tooth Comb isn’t just another lab tool; it’s a cornerstone for efficient and high-throughput sample processing. Manufactured by VWR, this system is designed to streamline electrophoresis, particularly for applications like PCR product analysis and plasmid screenings. Its defining feature? Its capacity to handle a significant volume of samples without sacrificing resolution.

In my previous role managing a high-volume genomics lab, we were constantly bottlenecked by our electrophoresis setup. We needed a system that could keep pace with our throughput, especially when processing samples from 96-well plates. I considered several options, but the VWR Maxi 20 Electrophoresis System‘s promise of high throughput and resolution caught my eye.

The system arrived well-packaged, with each component carefully secured. My initial impression was of robustness; the thick acrylic construction of the gel box and tray felt solid and durable. The combs, especially the 1 mm x 20-tooth combs, looked precise and well-made.

Compared to the older, smaller electrophoresis units we were using, this felt like a significant upgrade. We had also considered the Bio-Rad Sub-Cell GT system, and a similar system from Invitrogen, but the VWR system’s combination of price and features seemed the most compelling for our needs. I was excited to see if it could deliver on its promises.


Real-World Testing: Putting VWR Maxi 20 Electrophoresis System E1120-20MC-1 Combs 1 Mm x 20-Tooth Comb to the Test

First Use Experience

Our first test run involved analyzing PCR products from a large-scale genotyping project. We set up the gel, loaded samples using the 20-tooth combs, and ran the electrophoresis. The system performed flawlessly, providing crisp band separation even with a high sample load.

The ease of use was a pleasant surprise; the durable rubber casting gates eliminated the need for messy tape, and comb placement was straightforward thanks to the slots on the gel tray sides. Even with the high buffer volume of 1200mL, the system reached stable temperatures quickly. There were no unexpected buffer leaks or electrical issues.

Extended Use & Reliability

After several months of continuous use, the VWR Maxi 20 Electrophoresis System has proven to be incredibly reliable. We’ve run hundreds of gels, and the system continues to deliver consistent results. The acrylic construction has held up well, with no signs of cracking or warping.

Maintenance is simple; the platinum electrode cassettes are easily removed for cleaning. Compared to our previous systems, which required frequent repairs and recalibration, the VWR Maxi 20 Electrophoresis System has been a workhorse. It has exceeded our expectations and significantly improved our lab’s efficiency.

Breaking Down the Features of VWR Maxi 20 Electrophoresis System E1120-20MC-1 Combs 1 Mm x 20-Tooth Comb

Specifications

  • Dimensions: 23W x 39.5L x 9H cm (91/16 x 159/16 x 31/2“) – Compact footprint while accommodating large gels.
  • Buffer Volume: 1200 mL – Ensures stable running conditions and consistent results.
  • Max Sample Capacity: 450 – Ideal for high-throughput screening of samples.
  • Comb Type: 1 mm x 20-Tooth Comb – Creates wells suitable for loading significant sample volumes, useful for visualizing faint bands.
  • Gel Tray Size: 20x20cm (77/8×77/8″) – Offers ample space for separating complex mixtures.

These specifications are crucial because they directly impact the system’s ability to handle large sample volumes while maintaining high resolution. The 20-tooth combs, in particular, are vital for labs dealing with PCR products or plasmid screenings that require loading a substantial amount of sample into each well.

Performance & Functionality

The VWR Maxi 20 Electrophoresis System excels at its primary task: separating DNA fragments with high resolution. The system is easy to set up and use, thanks to the user-friendly design and clear instructions. The rubber casting gates eliminate the need for tape, and the adjustable combs allow for precise control over well depth.

One of the system’s strengths is its ability to handle a large number of samples simultaneously. The 20x20cm gel tray and 20-tooth combs make it possible to load up to 450 samples, which is a significant time-saver for high-throughput labs. There is very little distortion or band smearing, as I’ve witnessed with other systems I have used in the past.

Design & Ergonomics

The system’s design is practical and well-thought-out. The thick acrylic construction provides durability and leakproof performance. The gel box and tray are molded for seamless integration. The domed lid prevents condensation from dripping onto the gel, maintaining buffer concentration.

The user experience is enhanced by features like the “EasyLift” gel box lid, which is easily removed using the side tabs and pressure pads. There’s minimal learning curve even for new users to the equipment. This system is designed to maximize usability and efficiency in a lab environment.

Durability & Maintenance

The VWR Maxi 20 Electrophoresis System is built to last. The high-quality materials and robust construction ensure that it can withstand the rigors of daily use. Maintenance is straightforward; the platinum electrode cassettes can be easily removed for cleaning.

Given the components’ resistance to degradation, this equipment is designed to last long. This system is a solid long-term investment for any lab.

Accessories and Customization Options

The system comes with a 20x20cm gel tray, two 20-tooth, 1.5mm thick combs, two 40-tooth, 1.5mm thick combs, and well visualization strips. The availability of different comb sizes allows for customization based on specific application needs. While the system is primarily designed for standard electrophoresis applications, it is compatible with various commercially available reagents and electrophoresis buffers.

Pros and Cons of VWR Maxi 20 Electrophoresis System E1120-20MC-1 Combs 1 Mm x 20-Tooth Comb

Pros

  • High Throughput: The 20-tooth combs and large gel tray enable efficient processing of a large number of samples.
  • Excellent Resolution: Provides crisp band separation for accurate analysis of DNA fragments.
  • User-Friendly Design: Easy to set up, use, and maintain, with features like tape-free casting and adjustable combs.
  • Durable Construction: Built to withstand the rigors of daily use, ensuring long-term reliability.
  • Versatile: Suitable for a wide range of electrophoresis applications, including PCR product analysis, RFLP analysis, and plasmid screenings.

Cons

  • Buffer Volume: The 1200 mL buffer volume might require larger volumes of reagents compared to smaller systems.
  • Size: The 23W x 39.5L cm footprint may require more bench space than more compact electrophoresis systems.


Who Should Buy VWR Maxi 20 Electrophoresis System E1120-20MC-1 Combs 1 Mm x 20-Tooth Comb?

  • Perfect for: Molecular biology labs, genomics facilities, and research institutions requiring high-throughput electrophoresis for applications like PCR product analysis, RFLP analysis, and plasmid screenings.
  • Who should skip this product? Labs with very low sample throughput needs or those with limited bench space might find a smaller, more compact system more suitable.
  • Must-have accessories or modifications? High-quality electrophoresis buffers and DNA ladders are essential for optimal performance. An adjustable power supply is also crucial for consistent results.

Conclusion on VWR Maxi 20 Electrophoresis System E1120-20MC-1 Combs 1 Mm x 20-Tooth Comb

The VWR Maxi 20 Electrophoresis System E1120-20MC-1 Combs 1 Mm x 20-Tooth Comb is a robust, reliable, and efficient solution for high-throughput electrophoresis. Its user-friendly design, excellent resolution, and durable construction make it a valuable asset for any molecular biology lab. The 1 mm x 20-tooth combs are perfect for loading larger volumes, which is crucial for accurate visualization.

At $329.99, the price is justified by the system’s performance and long-term reliability. The increased efficiency and reduced maintenance costs will quickly offset the initial investment.

I would highly recommend the VWR Maxi 20 Electrophoresis System to any lab looking to streamline their electrophoresis workflow. Upgrade today and experience the difference!

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